Thermo‐Responsive Hydrogel Layers Imprinted with RGDS Peptide: A System for Harvesting Cell Sheets

Abstract

The efficient promotion of cell adhesion on a polymer surface and detachment of sheets of cells is possible with thermo-responsive cell culture substrates that are biofunctionalized through noncovalent molecular imprinting. The key is the thermo-responsive “specific binding” of the cell-adhesive peptide RGDS on the cell sheet harvest system (see picture). As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.