Outcome of children with high‐risk acute lymphoblastic leukemia (HR‐ALL): Nordic results on an intensive regimen with restricted central nervous system irradiation

Abstract

HR-ALL was successfully treated on the NOPHO-92 regimen, with a relatively low CNS relapse rate for non-irradiated children. WBC > or =200 x 10(9)/L and very slow response emerged as strong poor prognostic factors.