Extended Peripheral Zone Biopsy Schemes Increase Cancer Detection Rates and Minimize Variance in Prostate Specific Antigen and Age Related Cancer Rates: Results of a Community Multi-Practice Study

Abstract

This multi-practice community based study confirms the inadequacy of sextant biopsies and emphasizes the need for extended peripheral zone sampling of the lateral aspect of the prostate. Generally increasing patient age and PSA were associated with larger, higher grade tumors. Extended biopsy schemes minimize PSA and age related detection rates.