Concepedia

Laminin-5 chains are expressed differentially in metastatic and nonmetastatic hepatocellular carcinoma.

Gianluigi Giannelli, Emilia Fransvea, Carlo Bergamini, Felice Marinosci, Salvatore Antonaci

PubMed · 2003 · 98 citations · 28 references

Abstract

Ln-5 is associated with a more metastatic phenotype of HCC, and its detection could be an important finding both as an unfavorable prognostic factor and as a diagnostic marker for detecting micrometastasis in peritumoral tissues.

References

28

Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

Gianluigi Giannelli, Jutta Falk-Marzillier, O Schiraldi et al. · Science · 1997 · 1.2K citations

, , +13

A new nomenclature for the laminins

Robert E. Burgeson, Matthias Chiquet, Rainer Deutzmann et al. · Matrix Biology · 1994 · 753 citations

, , +5

Role of Cell Surface Metalloprotease Mt1-Mmp in Epithelial Cell Migration over Laminin-5

Naohiko Koshikawa, Gianluigi Giannelli, Vincenzo Cirulli et al. · The Journal of Cell Biology · 2000 · 649 citations · Full text

Molecular insights into cancer invasion: strategies for prevention and intervention.

Elise C. Kohn, Lance A. Liotta · PubMed · 1995 · 499 citations

, , +17

Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas.

C Pyke, Sirpa Salo, John Rømer et al. · PubMed · 1995 · 382 citations

, , +16