JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · 2015 · 20 citations · 12 references
MedicineDermatologyPathologyAnatomic PathologyGastroenterologyMolecular PathologyGenetic DisordersPigmentary DisordersHamartoma SyndromesHereditary Polyposis SyndromesIntestinal Polyposis Syndromes
Cronkhite-Canada syndrome (CCS) is an extremely rare non-inherited condition characterized by gastrointestinal hamartomatous polyposis, alopecia, onychodystrophy, hyperpigmentation, weight loss and diarrhoea. The aetiology is probably autoimmune and diagnosis is based on history, physical examination, endoscopic findings of gastrointestinal polyposis, and histology. The disease is very rare; approximately 450 cases of CCS have been reported worldwide. The author reports a case of CCS in an elderly Indian male.
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Generalized Gastrointestinal Polyposis
Leonard W. Cronkhite, Wilma Jeanne Canada · New England Journal of Medicine · 1955 · 450 citations
Medicine, Dermatology, Pathology +14
Cronkhite-Canada syndrome: epidemiological study of 110 cases reported in Japan.
Akira Gotō · PubMed · 1995 · 105 citations
Medicine, Dermatology, Psychiatry +10
Diffuse Gastrointestinal Polyposis with Ectodermal Changes
S. Jarnum, Herluf Jensen · Gastroenterology · 1966 · 95 citations
Medicine, Pathobiology, Pathology +12