Concepedia

Genetic Analysis of the Interleukin-18 System Highlights the Role of the Interleukin-18 Gene in Cardiovascular Disease

Laurence Tiret, Tiphaine Godefroy, Edith Lubos, Viviane Nicaud, David‐Alexandre Trégouët, Sandrine Barbaux, Renate B. Schnabel, Christoph Bickel, Christine Espinola–Klein, Odette Poirier,

Circulation · 2005 · 230 citations · 20 references

DOI

Abstract

Variations of the IL18 gene consistently influence circulating levels of IL-18 and clinical outcome in patients with coronary artery disease, which supports the hypothesis of a causal role of IL-18 in atherosclerosis and its complications.

References

20

Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men

Paul M. Ridker, Mary Cushman, Meir J. Stampfer et al. · New England Journal of Medicine · 1997 · 5.5K citations · Full text

C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease

John Danesh, Jeremy G. Wheeler, Gideon M. Hirschfield et al. · New England Journal of Medicine · 2004 · 2.9K citations · Full text

Inflammatory Markers and the Risk of Coronary Heart Disease in Men and Women

Jennifer K. Pai, Tobias Pischon, Jing Ma et al. · New England Journal of Medicine · 2004 · 1.2K citations · Full text

Interleukin-18 Binding Protein

Daniela Novick, Soo Hyun Kim, Giamila Fantuzzi et al. · Immunity · 1999 · 767 citations · Full text

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Translator's Introduction

Michael Shields · Method Journal of Lonergan Studies · 2001 · 752 citations