The first asymmetric synthesis of polyfunctionalized 4H-pyrans via Michael addition of malononitrile to 2-acyl acrylates

Tetrahedron report number 195 (R)- and (S)-2,3-0-isopropylideneglyceraldehyde in stereoselective organic synthesis

Janusz Jurczak, Stanisław Pikul, Tomasz Bauer · Tetrahedron · 1986 · 371 citations

Natural Sciences, Chemistry, Organic Chemistry +7

A new route to substituted 3-methoxycarbonyldihydropyrans; enantioselective synthesis of (–)-methyl elenolate

Susumi Hatakeyama, Noriko Ochi, Hirotoshi Numata et al. · Journal of the Chemical Society Chemical Communications · 1988 · 294 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Synthesis of 2,3-O-isopropylidene-D-glyceraldehyde in high chemical and optical purity: observations on the development of a practical bulk process

Christopher R. Schmid, Jerry D. Bryant, Mandy Dowlatzedah et al. · The Journal of Organic Chemistry · 1991 · 221 citations

Natural Sciences, Chemical Engineering, Chemistry +5

Total synthesis of natural products: The chiron approach

Thomas D. Inch · Carbohydrate Research · 1984 · 219 citations

Pharmacy, Chemistry, Medicinal Chemistry +15

Acyclic stereoselection. 30. Stereoselection in the Michael addition reaction. 2. Stereochemistry of the kinetic Michael reaction of amide enolates with enones

Clayton H. Heathcock, Mark Henderson, D. A. OARE et al. · The Journal of Organic Chemistry · 1985 · 53 citations

Natural Sciences, Chemistry, Catalysis +5