Highly Chemoselective Nickel‐Catalyzed Three‐Component Cross‐Trimerization of Three Distinct Alkynes Leading to 1,3‐Dien‐5‐ynes

Abstract

Cross-yned: The first highly chemoselective three-component cross-trimerization between a triisopropylsilylacetylene, an ether-functionalized unsymmetrical internal alkyne, and a symmetrical internal alkyne leading to a 1,3-dien-5-yne was achieved using a [Ni(cod)2]/PPh3 catalyst. This reaction is applicable for various internal alkynes with high regio- and stereoselectivities. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.