Antimicrobial Agents and Chemotherapy · 2002 · 118 citations · 17 references
AgricultureFood ScienceFood MicrobiologyMilk ChemistryMilk MicrobiologyAntimicrobial PropertiesEnzymatic Activity In MilkEscherichia ColiEscherichia Coli In MilkLuminescence MechanismsMetabolic Activity AssaysNitric OxideNitric Oxide Metabolism
Human and bovine milk inhibited the metabolic activity of Escherichia coli, as shown by luminescence monitoring of constructs expressing the luxCDABE genes. Inhibition was dependent on both xanthine oxidase (XO) activity and on the presence of nitrite, implying that XO-generated nitric oxide functions as an antibacterial agent.
17