Melatonin inhibits spontaneous and oxytocin-induced contractions of rat myometrium in vitro.

Abstract

Data from this study demonstrates that melatonin inhibits spontaneous and oxytocin-induced contractions of myometrium from pregnant and non-pregnant rats. Although the exact mechanism is not clear, melatonin-induced inhibition of myometrial contractions may results from its interactions with Ca(2+) channels.