The Analyst · 1982 · 12 citations · 0 references
PharmacyPharmaceutical AnalysisPharmaceuticsAnalytical ChemistryChromatographic AnalysisMass Spectrometric AnalysisAnalytical ChromatographyBioanalytical Method ValidationChromatographic Analysis Of PharmaceuticalsChromatographyDegradation Product AnalysisPharmaceutical StabilityAnalytical Detection LimitsAssay DeterminationChromatographic Separation Of DegradantsQuantitative DeterminationSteroid Degradation ProductsTablet Chromatographic AnalysisTablet Degradation AnalysisTablet Stability Assessment
A thin-layer chromatographic procedure is described for the separation and quantification of dipyrone in situ in the presence of three of the major degradation products. The repeatability and detection limits are given and the applicability of the assay in checking the stability of tablets and injections is shown.