Possible activation of the NO–cyclic GMP–protein kinase G–K+ channels pathway by gabapentin on the formalin test

Ethical guidelines for investigations of experimental pain in conscious animals

M. Zimmermann · Pain · 1983 · 7.8K citations

Medicine, Anesthesiology, Animal Sciences +14

Characterization of three inhibitors of endothelial nitric oxide synthase <i>in vitro</i> and <i>in vivo</i>

Daryl D. Rees, Richard Palmer, Richard Schulz et al. · British Journal of Pharmacology · 1990 · 1.9K citations · Full text

Medicine, Cardiology, Pharmacology +12

The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the α2δ Subunit of a Calcium Channel

N S Gee, Jason P. Brown, Visaka U.K. Dissanayake et al. · Journal of Biological Chemistry · 1996 · 1.2K citations · Full text

Medicine, Neuroscience, Pharmacology +15

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

Hiroshi Kase, Kazuyuki Iwahashi, Satoshi Nakanishi et al. · Biochemical and Biophysical Research Communications · 1987 · 942 citations

Life Sciences, Medicinal Chemistry, Pharmacology +13

Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.

Annika B. Malmberg, T L Yaksh · Journal of Pharmacology and Experimental Therapeutics · 1992 · 653 citations

Medicine, Pharmacology, Pharmacotherapy +17