Concepedia

Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+Electronic supplementary information (ESI) available: method for determining equilibrium binding constants and representative spectroscopic data for each experiment. See http://www.rsc.org/suppdata/cc/b3/b316917k/

Janice R. Aldrich‐Wright, Craig R. Brodie, Edith C. Glazer, Nathan W. Luedtke, Lev Elson‐Schwab, Yitzhak Tor

Chemical Communications · 2004 · 50 citations · 10 references

DOI

Abstract

Symmetrical homometallic dinuclear complexes of the type [(Ru(dpq)2)2(phen-SOS-phen)]4+, with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)2(phen)]2+-based sub-units, have DNA dissociation constants (Kd) in the nM range.

References

10

Interaction of .DELTA.- and .LAMBDA.-[Ru(phen)2DPPZ]2+ with DNA: A Calorimetric and Equilibrium Binding Study

Ihtshamul Haq, Per Lincoln, Dongchul Suh et al. · Journal of the American Chemical Society · 1995 · 489 citations

Oxidative Damage by Ruthenium Complexes Containing the Dipyridophenazine Ligand or Its Derivatives:  A Focus on Intercalation

Sarah Delaney, M. Pascaly, Pratip K. Bhattacharya et al. · Inorganic Chemistry · 2002 · 235 citations

DNA-Binding of Semirigid Binuclear Ruthenium Complex Δ,Δ-[μ-(11,11‘-bidppz)(phen)<sub>4</sub>Ru<sub>2</sub>]<sup>4+</sup>:  Extremely Slow Intercalation Kinetics

L. Marcus Wilhelmsson, Fredrik Westerlund, Per Lincoln et al. · Journal of the American Chemical Society · 2002 · 185 citations · Full text

, , +15

Photophysics of Ru(phen)<sub>2</sub>(PHEHAT)<sup>2+</sup>:  A Novel “Light Switch” for DNA and Photo-oxidant for Mononucleotides

Cécile Moucheron, Andrée Kirsch‐De Mesmaeker, Sylvia Choua · Inorganic Chemistry · 1997 · 184 citations

DNA interactions with substitution-inert transition metal ion complexes.

Bengt Nordén, Per Lincoln, Björn Åkerman et al. · PubMed · 1996 · 108 citations

, , +6