Evaluating the 'all-comers' design: a comparison of participants in two 'all-comers' PCI trials with non-participants

Abstract

Applying the all-comers design did not result in inclusion of all consecutive patients, as only half of the target population was enrolled. It should be noted, however, that this design included more patients than observed in classical RCTs. AC-RCT participants and non-participants were different in terms of baseline characteristics and outcome.