Journal of orthopaedic surgery · 2002 · 227 citations · 19 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryBone GraftingImplant SurgeryOrthopaedic BiomaterialsBone InfectionsBone SubstitutesChronic Bone InfectionOsteomyelitisOsteomyelitis ManagementSynthetic Bone SubstitutesAntibiotic-eluting ImplantsAntibiotic-loaded ImplantsAntimicrobial-impregnated ImplantsBone Void FillingCalcium Sulfate Bone SubstitutesDead Space ClosureImplant - Tissue Interface
The use of local antibiotics from a biodegradable implant for chronic osteomyelitis is an attractive alternative. The implant delivers high tissue levels, obliterates dead space, aids bone repair and does not need to be removed. The purpose of this paper is to review our early clinical experience with custom-made calcium sulfate (Osteoset bone void filler) antibiotic-impregnated implants.
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Clinical Orthopaedics and Related Research
TL · The American Journal of the Medical Sciences · 1966 · 895 citations
John Blaha, JASON H. CALHOUN, Carl L. Nelson et al. · Clinical Orthopaedics and Related Research · 1993 · 130 citations
Medicine, Orthopaedic Surgery, Antimicrobial Pharmacology +10