The Functional Status of the <i>Helicobacter pylori sabB</i> Adhesin Gene as a Putative Marker for Disease Outcome

Abstract

The off-status of sabB was found to be associated with duodenal ulcer disease, and thus represents a putative marker for disease outcome. Assuming that SabB is involved in bacterial adhesion, this association suggests that adherent H. pylori are more prone to elimination by the host immune system.