Roles of Prostaglandin E <sub>2</sub> –EP3/EP4 Receptor Signaling in the Enhancement of Lymphangiogenesis During Fibroblast Growth Factor-2–Induced Granulation Formation - Concepedia

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Roles of Prostaglandin E <sub>2</sub> –EP3/EP4 Receptor Signaling in the Enhancement of Lymphangiogenesis During Fibroblast Growth Factor-2–Induced Granulation Formation

DOI Full Paper Access

61

Citations

58

References

2011

Year

Kanako Hosono, Tatsunori Suzuki, Hideaki Tamaki, Hiroyuki Sakagami, Izumi Hayashi, Shuh Narumiya, Kari Alitalo, Masataka Majima

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Our findings suggest that COX-2 and EP3/EP4 signaling contributes to lymphangiogenesis in proliferative inflammation, possibly via induction of VEGF-C and VEGF-D, and may become a therapeutic target for controlling lymphangiogenesis.

References

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