Anogenital Distance and Penile Length in Infants with Hypospadias or Cryptorchidism:Comparison with Normative Data

Abstract

In the study population, AGD and penile length were reduced in boys with hypospadias or cryptorchidism relative to normative data derived from a longitudinal birth cohort. The findings support the use of AGD as a quantitative biomarker to examine the prenatal effects of exposure to endocrine disruptors on the development of the male reproductive tract.