British Journal of Ophthalmology · 2011 · 228 citations · 19 references
Health ProfessionsOphthalmologySurgeryClinical OptometryOphthalmic SurgerySensorsGlaucomaGlaucoma MonitoringIntraocular Pressure MeasurementOcular BiometrySoft Contact Lenses24-Hour Intraocular Pressure MonitoringAnterior Corneal CurvatureContinuous Pressure MonitoringCorneal Curvature MeasurementIntraocular Pressure AssessmentOpen-angle Glaucoma ManagementPrimary Open-angle Glaucoma MonitoringSerious Adverse Events
The authors report their initial clinical results with a novel wireless ocular telemetry sensor (OTS) (Sensimed AG, Switzerland) for continuous intraocular pressure (IOP) monitoring in patients with open angle glaucoma. This was a prospective, observational cohort of 15 patients. The OTS is a disposable silicone contact lens with an embedded micro-electromechanical system, which measures changes in corneal curvature induced by variations in IOP. An antenna, mounted around the eye, receives the data, which are then transmitted to a recorder. A signal was recorded in all patients. Thirteen (87%) patients completed 24-h IOP monitoring: one patient discontinued IOP monitoring due to device intolerance, and incomplete recordings were obtained in a second patient due to technical device malfunction. In 9/13 (69%) patients, the highest signals were recorded during the nocturnal period. No serious adverse events were recorded. The OTS shows good safety and functionality to monitor IOP fluctuations in patients over 24 h. This technology has the potential to provide hitherto unobtainable data on the chronobiology of IOP, possibly leading to improved care of glaucoma patients.
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Nocturnal elevation of intraocular pressure in young adults.
J H Liu, D F Kripke, R E Hoffman et al. · PubMed · 1998 · 281 citations