An alteration in the liver microsomal membrane of the rat following paracetamol overdose

Abstract

Fluorescence polarization of dansyl chloride covalently labelled microsomal membranes revealed an alteration in rat liver microsomal membranes following as a consequence of a paracetamol overdose. This suggests that dansyl chloride would be a useful probe in the study of the effects of paracetamol on microsomal membranes.