Noninternalizing Monoclonal Antibodies Are Suitable Candidates for ¹²⁵I Radioimmunotherapy of Small-Volume Peritoneal Carcinomatosis

Abstract

This study indicates that (125)I-labeled noninternalizing mAbs could be suitable for radioimmunotherapy of small solid tumors and that the use of internalizing mAbs should not be considered as a requirement for the success of treatments with (125)I Auger electrons.