Novel Use of Glucagon in a Closed-Loop System for Prevention of Hypoglycemia in Type 1 Diabetes

Jessica R. Castle, J. Michael Engle, Joseph El Youssef, Ryan G. Massoud, Kevin C.J. Yuen, Ryland Kagan, W. Kenneth Ward

Diabetes Care · 2010 · 230 citations · 17 references

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Abstract

During closed-loop treatment in subjects with type 1 diabetes, high-gain pulses of glucagon decreased the frequency of hypoglycemia. Larger and longer-term studies will be required to assess the effect of ongoing glucagon treatment on overall glycemic control.

References

17