Concepedia

Palladium(0)‐Catalyzed Hydroalkoxylation of Hexafluoropropene: Synthesis of Hydrofluoroethers under Neutral Conditions

Yasuhisa Matsukawa, Junji Mizukado, Hengdao Quan, Masanori Tamura, Akira Sekiya

Angewandte Chemie International Edition · 2005 · 35 citations · 12 references

DOI

Concepts

Abstract

No vinyl ether by-products are formed in the palladium(0)-complex catalyzed hydroalkoxylation of hexafluoropropene (see scheme). Saturated hydrofluoroethers are selectively synthesized with alcohols or phenols under neutral conditions in the presence of [Pd(PPh3)4]/dppb. dppb=1,4-bis(diphenylphosphanyl)butane.

References

12

Catalytic Markovnikov and anti‐Markovnikov Functionalization of Alkenes and Alkynes: Recent Developments and Trends

Matthias Beller, Jayasree Seayad, Annegret Tillack et al. · Angewandte Chemie International Edition · 2004 · 1.1K citations · Full text

, , +14

The potential of hydrofluoroethers to replace CFCs, HCFCs and PFCs

Akira Sekiya, Susumu Misaki · Journal of Fluorine Chemistry · 2000 · 213 citations

, , +3

Oligomerization and dimerization of butadiene under homogeneous catalysis. Reaction with nucleophiles and the synthesis of 1,3,7-octatriene

Edgar J. Smutny · Journal of the American Chemical Society · 1967 · 208 citations

, , +5

Palladium-Catalyzed Hydroalkoxylation of Methylenecyclopropanes

Drexel H. Camacho, Itaru Nakamura, Shinichi Saito et al. · Angewandte Chemie International Edition · 1999 · 83 citations

, , +13

‘Anti-Wacker’-type hydroalkoxylation of diynes catalyzed by palladium(0)

Drexel H. Camacho, Shinichi Saito, Yoshinori Yamamoto · Tetrahedron Letters · 2002 · 47 citations

, , +10