Converging Evidence for the Association of Functional Genetic Variation in the Serotonin Receptor 2a Gene With Prefrontal Function and Olanzapine Treatment - Concepedia

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Converging Evidence for the Association of Functional Genetic Variation in the Serotonin Receptor 2a Gene With Prefrontal Function and Olanzapine Treatment

49

Citations

56

References

2013

Year

Giuseppe Blasi, Caterina De Virgilio, Apostolos Papazacharias, Paolo Taurisano, Barbara Gelao, Leonardo Fazio, Gianluca Ursini, Lorenzo Sinibaldi, Ileana Andriola, Rita Masellis,

JAMA Psychiatry

Abstract

Our results suggest that HTR2A rs6314 affects 5-HT2AR expression and functionally contributes to genetic modulation of known endophenotypes of schizophrenia-like higher-level cognitive behaviors and related prefrontal activity, as well as response to treatment with olanzapine.

References

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