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Evaluation of (R)-[11C]verapamil as PET tracer of P-glycoprotein function in the blood–brain barrier: kinetics and metabolism in the rat

Gert Luurtsema, Carla F.M. Molthoff, Robert C. Schuit, Albert D. Windhorst, Adriaan A. Lammertsma, Eric J. F. Franssen

Nuclear Medicine and Biology · 2005 · 112 citations · 32 references

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32

Pharmacogenomics — Drug Disposition, Drug Targets, and Side Effects

William E. Evans, Howard L. McLeod · New England Journal of Medicine · 2003 · 1.8K citations

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Deposition of Alzheimer's ??-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans

Silke Vogelgesang, Ingolf Cascorbi, Eike Schroeder et al. · Pharmacogenetics · 2002 · 340 citations

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Characterization of the Major Metabolites of Verapamil as Substrates and Inhibitors of P-glycoprotein

Christiane Pauli‐Magnus, Oliver von Richter, Oliver Burk et al. · Journal of Pharmacology and Experimental Therapeutics · 2000 · 204 citations · Full text

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Identification of P450 enzymes involved in metabolism of verapamil in humans

H. Kroemer, Jean‐Charles Gautier, Philippe Beaune et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1993 · 203 citations

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Stereoselective binding of 11C-raclopride in living human brain ? a search for extrastriatal central D2-dopamine receptors by PET

Lars Farde, Stefan Pauli, Håkan Hall et al. · Psychopharmacology · 1988 · 202 citations

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