Muscle & Nerve · 2013 · 70 citations · 6 references
MedicineNeurologyRadiologyDiagnostic ImagingUltrasonographyUltrasoundAmyotrophic Lateral SclerosisDiagnostic UltrasonographyInclusion Body MyositisMuscle DisordersMusculoskeletal UltrasonographyMusculoskeletal UltrasoundAmyotrophic Lateral Sclerosis PathologyInclusion Body LesionsMuscle Ultrasound Echo IntensitySporadic Amyotrophic Lateral SclerosisSporadic Inclusion Body MyositisUltrasound Muscle ImagingUltrasound-based Muscle AssessmentWrist Ultrasonography
INTRODUCTION: In this study we aimed to clarify whether muscle ultrasound (US) of the forearm can be used to differentiate between patients with sporadic inclusion body myositis (s-IBM) and those with s-IBM-mimicking diseases. METHODS: We compared the echo intensity (EI) of the flexor digitorum profundus (FDP) muscle and the flexor carpi ulnaris (FCU) muscles in patients with s-IBM (n = 6), polymyositis/dermatomyositis (PM/DM; n = 6), and amyotrophic lateral sclerosis (ALS; n = 6). RESULTS: We identified EI abnormalities in 100% of patients with s-IBM, 33% of those with PM/DM, and 33% of those with ALS. An "FDP-FCU echogenicity contrast," a US pattern involving a higher EI in the FDP than in the FCU, was observed in all patients with s-IBM, but in none of those with PM/DM or ALS. CONCLUSIONS: FDP-FCU echogenicity contrast in muscle US is a sensitive diagnostic indicator of s-IBM.
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Jessica E. Hoogendijk, Anthony A. Amato, Bryan Lecky et al. · Neuromuscular Disorders · 2004 · 937 citations
Ultrasound imaging in the diagnosis of muscle disease
J Z Heckmatt, S. Leeman, Victor Dubowitz · The Journal of Pediatrics · 1982 · 454 citations
Andrew Eisen, Kenneth Berry, Gillian Gibson · Neurology · 1983 · 95 citations