Catalytic Gold Nanoparticles for Nanoplasmonic Detection of DNA Hybridization

Abstract

DNA hybridization can finely regulate the intrinsic glucose oxidase like catalytic activity of AuNPs owing to the marked difference in adsorption of single- and double-stranded DNA on its surface. A sensing strategy for DNA and microRNA is presented; in a different approach, this DNA-regulated AuNP catalysis was coupled with AuNP-mediated seed growth, which was monitored in real time and at a single-nanoparticle level. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.