Poly(propylene imine) Dendrimers: Large‐Scale Synthesis by Hetereogeneously Catalyzed Hydrogenations

Abstract

In kilogram quantities ; pure poly(propylene imine) dendrimers can be prepared in an extremely simple reaction sequence comprising Michael addition (primary amines to acrylonitrile) and heterogeneous hydrogenation with a Raney cobalt catalyst. Both steps proceed quantitatively and selectively and can be employed with many core and end groups.