Prolonged Recovery Rate of CB1 Receptor Adaptation after Cessation of Long-Term Cannabinoid Administration

Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB ₁ Receptor Knockout Mice

Catherine Ledent, Olga Valverde, G Cossu et al. · Science · 1999 · 3.6K citations

Medicine, Neuroscience, Pharmacology +15

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

Miles Herkenham, A B Lynn, MR Johnson et al. · Journal of Neuroscience · 1991 · 2.2K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system

K Tsou, Sean M. Brown, M.Clara Sañudo-Peña et al. · Neuroscience · 1998 · 1.6K citations

Life Sciences, Neurobiology, Neuroscience +11

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

Andreas Zimmer, Anne Zimmer, Andrea G. Hohmann et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

Medicine, Neuroscience, Pharmacology +9

Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor

Ken Mackie, Y Lai, R. Westenbroek et al. · Journal of Neuroscience · 1995 · 624 citations · Full text

Medicine, Neurobiology, Pharmacology +12