Photoacoustic Imaging of the Breast Using the Twente Photoacoustic Mammoscope: Present Status and Future Perspectives

Daniele Piras, Wenfeng Xia, Wiendelt Steenbergen, Ton G. van Leeuwen, Srirang Manohar

IEEE Journal of Selected Topics in Quantum Electronics · 2009 · 116 citations · 37 references

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Concepts

TL;DR

The Twente photoacoustic mammoscope (PAM) employs 1064‑nm pulsed light to generate photoacoustic signals. The study consolidates the key specifications of the PAM system. The PAM detects signals with a 590‑element planar ultrasound sensor array, reconstructs images via delay‑and‑sum beamforming, and acquires data in forward mode with mild breast compression and ultrasound gel. Imaging of two infiltrating ductal carcinoma cases and one cyst demonstrated the system’s capability, and the authors discuss current limitations and future improvements.

Abstract

The Twente photoacoustic mammoscope (PAM) uses pulsed light at 1064 nm to excite PA signals. Detection is using a planar 590-element ultrasound (US) sensor matrix. Image reconstruction uses a delay-and-sum beamforming algorithm. Measurements are performed in the forward mode, with mild compression of the breast against the detector with US coupling gel. We consolidate the most important specifications of the system. Furthermore, we discuss in detail the results of imaging two cases of infiltrating ductal carcinoma and one case of a cyst. We critically discuss the features of the present embodiment and present plans for its improvement.

References

37