Concepedia

Publication | Closed Access

Interferon‐inducible cholesterol‐25‐hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation

DOI

85

Citations

39

References

2015

Year

Anggakusuma, Inés Romero‐Brey, Carola Berger, Che C. Colpitts, Tujana Boldanova, Michael Engelmann, Daniel Tödt, Paula Monteiro Perin, Patrick Behrendt, Florian W. R. Vondran,
Hepatology

Abstract

Infection with HCV causes up-regulation of interferon-inducible CH25H in vivo, and its product, 25HC, restricts HCV primarily at the level of RNA replication by preventing formation of the viral replication factory.

References

YearCitations

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