Journal of Bone and Joint Surgery - British Volume · 2005 · 146 citations · 13 references
MedicineOrthopaedic SurgerySurgeryMetastasisOrthopaedic OncologySurgical OncologyMalignant TumorsMargin AssessmentPelvic Tumor SurgeryPelvic TumorsSarcoma SurgeryTumor MarginsChondrosarcoma GradingChondrosarcoma SurgeryClose Surgical MarginsLocal Tumor RecurrenceNegative Surgical MarginsOperative MorbidityPelvic ChondrosarcomaSurgical Resection Margins
We reviewed 124 patients with a conventional pelvic chondrosarcoma who had been treated over a period of 20 years. We recorded the type of tumour (central or peripheral), type of operation (limb salvage surgery or hemipelvectomy), the grade of tumour, local recurrence and/or metastases, in order to identify the factors which might influence survival. More satisfactory surgical margins were achieved for central tumours or in those patients treated by hemipelvectomy. However, grade 1 tumours, whatever the course, did not develop metastases or cause death, while grade 3 tumours had the worst outcome and prognosis. Central, high-grade tumours require aggressive surgical treatment in order to achieve adequate surgical margins, particularly in those lesions located close to the sacroiliac joint. By contrast, grade 1 peripheral chondrosarcomas may be treated with contaminated margins in order to reduce operative morbidity, but without reducing survival.
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Francis Lee, Henry J. Mankin, Gertrude Fondren et al. · Journal of Bone and Joint Surgery · 1999 · 424 citations
Primary chondrosarcoma of long bones and limb girdles
Johannes Bj�rnsson, Richard A. McLeod, K. Krishnan Unni et al. · Cancer · 1998 · 296 citations · Full text
Chondrosarcoma of the pelvis: Prognostic factors for 67 patients treated with definitive surgery
Dhiren S. Sheth, Alan W. Yasko, Mark E. Johnson et al. · Cancer · 1996 · 163 citations · Full text