Studies on a new aminoglycoside antibiotic, dactimicin. I. Producing organism and fermentation.

Abstract

The producing organism of a new antibiotic, dactimicin, is described. The presence of finger-shaped sporangia bearing motile spores, the absence of aerial mycelium and its cell wall of type II, ascribe this organism to the genus Dactylosporangium. The cultural and physiological features distinguish this organism from all the described Dactylosporangium species. Therefore, it is considered to be a new species for which the name Dactylosporangium matsuzakiense sp. nov. is proposed. Fermentation of dactimicin is also described.