Publication | Open Access

Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: Key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action

Molecular PharmacologyMedicineApoptosisCell DeathCellular PharmacologyAnti-cancer Agentδ-Lactone RingPharmacologyCell BiologyPharmaceutical ChemistryTumor BiologyDrug DiscoveryU-937 CellsDifferentiation-inducing Potency