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Iron‐Containing Nucleoside Analogues with Pronounced Apoptosis‐Inducing Activity
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Citations
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References
2004
Year
Bioorganic ChemistryBjab Tumor CellsChemoprevention StrategyIron MetabolismApoptosisCell DeathChemical BiologyRedox BiologyOxidative StressMedicinal ChemistryBioorganometallic ChemistryAnti-cancer AgentBioactive Organometallic CompoundsBiochemistryNucleoside AnaloguesIron-containing Nucleoside AnaloguesReactive Oxygen SpeciePharmacologyNatural Product SynthesisNatural SciencesMedicine
Bioactive organometallic compounds: Iron-containing nucleoside analogues, which can be stereoselectively synthesized in a few steps starting from simple carbohydrates, cause tumor cells to undergo apoptosis (programmed cell death; see picture for the typical morphological characteristics of BJAB tumor cells after apoptosis). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z53132_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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