Extensive subcutaneous calcification following injections of pitressin tannate

Abstract

The occurrence of soft tissue opacities following the injection of radiopaque substances is well recognised. The classical example is bismuth, which was commonly used in the treatment of syphilis. Less well recognised is dystrophic calcification following the injection of nonradiopaque materials such as calcium gluconate inadvertently injected into the soft tissues (Berger et al, 1974) or quinine given intramuscularly for the treatment of malaria (Brown, 1945).