Transcript Profiling of Periodontal Fibroblasts and Osteoblasts

Abstract

Our results indicate that PDL fibroblasts are distinct from either gingival or dermal fibroblasts or osteoblasts. In general, PDL and gingival fibroblasts displayed greater similarity to each other than either displayed toward dermal fibroblasts. Furthermore, both gingival and PDL fibroblasts displayed greater similarity to osteoblasts than to dermal fibroblasts, possibly reflecting their common origin (the neural crest).