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Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: Synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods

Medicinal ChemistryBiosynthesisGlycosylationBiochemistryMedicineBiocatalysisNatural SciencesGlycobiologyCrystallographic MethodsGlycogen PhosphorylasePharmacologyEnzymatic ModificationPharmaceutical ChemistryDrug DiscoveryNatural Product Synthesis