CLINICAL AND ELECTROENCEPHALOGRAM INVESTIGATION ON LARGACTIL IN PSYCHOSIS (PRELIMINARY STUDY)

Abstract

1. Experimental investigations have been carried out with Largactil on chronic and acute mental patients. 2. The over-all improvement in chronic cases was 69% and in acute cases 60%. 3. However, the transitory effects in acute cases indicate that while Largactil is extremely valuable in chronic psychosis, in acute psychotic breakdowns, it has value only as a sedative. 4. Electroencephalogram investigations showed that Largactil markedly decreases the muscle artefacts, decreases the frequency, and increases the voltage, causing a mild progressive synchronization and, in epileptics, it lessens the convulsive threshold. 5. In spastics it decreases spasticity through intravenous route, as tested by electromyogram.