Evaluation of t‐PA, PAI‐2, IL‐1<i>β</i> and PGE₂ in gingival crevicular fluid of rheumatoid arthritis patients with periodontal disease

Abstract

The coexistence of RA and periodontitis does not seem to affect clinical periodontal findings or systemic markers of RA. Similar inflammatory mediator levels in RA and PD groups, despite the long-term usage of corticosteroids, non-steroidal anti-inflammatory drugs, suggest that RA patients may have a propensity to overproduce these inflammatory mediators.