Publication | Closed Access
Pd-mediated new synthesis of pyrroles: their evaluation as potential inhibitors of phosphodiesterase 4
63
Citations
12
References
2011
Year
Combinatorial ChemistryPhosphodiesterase 4Organic ChemistryChemistryHeterocycle ChemistryPharmaceutical ChemistryMedicinal ChemistryPd-mediated New SynthesisFunctionalized PyrrolesSingle PotCross-coupling ReactionBiochemistrySynthesis MethodPharmacologyNatural SciencesPotential InhibitorsMedicineSynthetic ChemistryDrug Discovery
A sequential Pd-mediated multi-component reaction followed by Suzuki or Heck or Sonogashira coupling in a single pot has been developed for the synthesis of functionalized pyrroles as potential inhibitors of PDE4.
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