Anionic Cycloaddition on Electron‐Deficient Alkynes–Synthesis and Stereochemistry of 3‐Pyrroline‐3‐carboxylic Acid <i>N,N</i>‐Dimethylamides

Abstract

An entry to 3-pyrroline derivatives such as (2), with defined spatial arrangement of the substituents on C-2 and C-5, is opened up by the reaction of (1) with electron-deficient alkynes. Compounds of type (2) are of interest because of their biological activity.