Significance of elevated gingival crevicular fluid tumor necrosis factor-α and interleukin-8 levels in chronic hemodialysis patients with periodontal disease

Abstract

The levels of TNF-alpha and IL-8 in gingival crevicular fluid were significantly higher in HD patients than in controls. There were strong, positive correlations between clinical periodontal parameters and the levels of inflammatory cytokines in gingival crevicular fluid from the HD patients.