Science · 2003 · 290 citations · 16 references
Life SciencesPlant BiologyPlant SciencesGene ExpressionPlant Developmental BiologyPlant Molecular BiologyPlant Gene ExpressionPlant Hormone SignalingPlant HormonesPlant Transcriptional RegulationRoot DevelopmentRoot MorphologyEpidermal CellsGene Circuit Regulatory ArchitecturePhospholipid SignalingRoot Development RegulationRoot Development Signaling PathwaysRoot Hair DevelopmentRoot HairsRoot Initiation
The root-hair pattern of Arabidopsis is determined through a regulatory circuit composed of transcription factor genes. The homeobox gene GLABRA2 (GL2) has been considered a key component, acting farthest downstream in this regulation. GL2 modified to include a transactivating function caused epidermal cells to develop ectopic root hairs or root hair-like structures. With this system, the phospholipase Dzeta1 gene (AtPLDzeta1) was identified as a direct target of GL2. Inducible expression of AtPLDzeta1 promoted ectopic root-hair initiation. We conclude that GL2 exerts its regulatory effect on root-hair development through modulation of phospholipid signaling.
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