Concepedia

Prognostic Value of a Combined Estrogen Receptor, Progesterone Receptor, Ki-67, and Human Epidermal Growth Factor Receptor 2 Immunohistochemical Score and Comparison With the Genomic Health Recurrence Score in Early Breast Cancer

Jack Cuzick, Mitch Dowsett, Sílvia Pineda, Christopher Wale, Janine Salter, Emma M. Quinn, Lila Zabaglo, Elizabeth Mallon, Andrew R. Green, Ian O. Ellis,

Journal of Clinical Oncology · 2011 · 737 citations · 15 references

DOI

Abstract

This study suggests that the amount of prognostic information contained in four widely performed IHC assays is similar to that in the GHI-RS. Additional studies are needed to determine the general applicability of the IHC4 score.

References

15

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer

Antonio C. Wolff, M. Elizabeth H. Hammond, Jared N. Schwartz et al. · Journal of Clinical Oncology · 2006 · 4.5K citations

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer

M. Elizabeth H. Hammond, Daniel F. Hayes, Mitch Dowsett et al. · Journal of Clinical Oncology · 2010 · 4.2K citations · Full text

Gene Expression and Benefit of Chemotherapy in Women With Node-Negative, Estrogen Receptor–Positive Breast Cancer

Soonmyung Paik, Gong Tang, Steven Shak et al. · Journal of Clinical Oncology · 2006 · 2.6K citations

Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial

Jack Cuzick, Ivana Šestak, Michael Baum et al. · The Lancet Oncology · 2010 · 1.7K citations

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Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial

Kathy S. Albain, William E. Barlow, Steven Shak et al. · The Lancet Oncology · 2009 · 1.4K citations · Full text

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