IEEE Photonics Technology Letters · 2004 · 35 citations · 9 references
EngineeringBioengineeringBiomedical EngineeringBiomaterialsBiomedical OpticsBiosensorsBiomedical SensorsNanosensorsOptical BiosensingOptical BiosensorsPlasmonicsPolarization OpticsBiosensor DevelopmentBiosensor MiniaturizationPlasmonic BiosensingPlasmonic BiosensorsSurface Plasmon Resonance BiosensingSurface Plasmon Resonance BiosensorsWaveguide BiosensorsWaveguide-based Biosensing
A new surface-plasmon-resonance (SPR) waveguide biosensor with the capability of bipolarization wavelength interrogation is presented. In the conventional SPR biosensors, only the transverse magnetic (TM)-polarized lightwave can couple with the surface plasma wave. The proposed SPR biosensor can make both the TM- and the transverse electric (TE)-polarized lightwave to produce the SPR. Therefore, two kinds of biomaterials can be separately detected by the signals from the TM- and the TE-polarized modes, and the number of detectable materials in a single chip can be doubled. Human serum albumin is coated on the device to sense the concentration of beta-blocker. Experimental results show that the concentration of beta-blocker is related to the SPR wavelength shift at a rate of 0.08 and 0.027 nm/ppm for the TM- and the TE-polarized modes, respectively.
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Single-mode optical fibre surface plasma wave chemical sensor
A.J.C. Tubb, F.P. Payne, Roger B. Millington et al. · Sensors and Actuators B Chemical · 1997 · 96 citations