NF-κB Activation and Fas Ligand Overexpression in Blood and Plaques of Patients With Carotid Atherosclerosis

Abstract

NF-kappaB activation and FasL overexpression occur in PBMCs and atherosclerotic lesions of patients with carotid stenosis. The NF-kappaB-FasL pathway could be involved in the mechanisms underlying plaque instability in humans.