Journal of Cutaneous Laser Therapy · 2000 · 211 citations · 16 references
MedicineDermatologySurgeryAesthetic SurgeryBiomedical OpticsBiophotonicsBiomedical Laser ApplicationsLaser ResurfacingLaser SurgeryLaser-tissue InteractionSkin RejuvenationWrinkle ReductionAblative Laser TherapyMicrofibrillar CollagenNon-ablative Laser ResurfacingNon-ablative Laser SurgeryNon-ablative Laser TherapyTreatment ParametersType I Collagen ProductionWrinkle Correction
BACKGROUND AND OBJECTIVES: Skin resurfacing and wrinkle removal is a large medical laser market. However, the rate of undesirable side effects is high and sometimes is not warranted by the aesthetic improvement observed. The authors have evaluated the potential benefits of an approach to selective non-ablative wrinkle reduction. MATERIALS AND METHODS: This technique selectively targets the microvasculature which plays a key role in the stimulation of enhanced collagen production. RESULTS: The study reported shows that application of the laser parameters described enhances collagen production by an average of 84%, measured 72 hours after a single laser treatment. This is achieved whilst leaving the skin barrier intact and with no adverse pigmentary changes. The study further shows that a cosmetic improvement is observed with an average value of 1.88 reduction in wrinkle appearance as measured on the Fitzpatrick Wrinkle Severity scale. This improvement was achieved with one brief treatment and no reported incidence of side effects. CONCLUSION: In conclusion, the treatment modality described may be a new approach to the treatment of wrinkles.
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Pulsed Carbon Dioxide Laser Resurfacing of Photoaged Facial Skin
Richard E. Fitzpatrick · Archives of Dermatology · 1996 · 635 citations
Medicine, Dermatology, Surgery +17
Pulsed dye laser therapy for sun damaged skin
Brian D. Zelickson, Suzanne L. Kilmer, Eric F. Bernstein et al. · Lasers in Surgery and Medicine · 1999 · 254 citations · Full text
Medicine, Dermatology, Surgery +15
Cryogen Spray Cooling in Combination With Nonablative Laser Treatment of Facial Rhytides
Kristen M. Kelly, J. Stuart Nelson, Gary Lask et al. · Archives of Dermatology · 1999 · 216 citations · Full text
Medicine, Dermatology, Surgery +17