KCNQ Channels in Nociceptive Cold-Sensing Trigeminal Ganglion Neurons as Therapeutic Targets for Treating Orofacial Cold Hyperalgesia

Abstract

Taken together, these findings indicate that KCNQ channel plays a significant role in controlling cold sensitivity and is a therapeutic target for alleviating trigeminal neuropathic pain that manifests orofacial cold hyperalgesia.