A new indole alkaloid isolated from Tabernaemontana hystrix steud (Apocynaceae)

Abstract

A new alkaloid, named hystrixnine (1), and five known indole alkaloids, ibogamine (2), olivacine (3), affinine (4), affinisine (5) and Nb-methylaffinisine (6), were isolated from the root bark of Tabernaemontana hystrix. The known triterpenes alpha-amyrin acetate, beta-amyrin acetate and lupeol acetate were also identified. The structures of the compounds were elucidated based on spectroscopic studies.